Vaccinations against 10 major pathogens have a substantial impact on public health in low-income and middle-income countries (LMICs), according to new modelling research published in The Lancet. The study estimated that from 2000 to 2019 vaccinations have prevented 37 million deaths, and that this figure will increase to 69 million deaths for the period 2000-2030.
The study assessed impact of vaccination programmes against ten pathogens in 98 LMICs: hepatitis B (HepB), Haemophilus influenzae type b (Hib), human papillomavirus (HPV), Japanese encephalitis (JE), measles, Neisseria meningitidis serogroup A (MenA), Streptococcus pneumoniae, rotavirus, rubella virus and yellow fever virus (YF).
In terms of the impact of vaccination over the lifetime of people born between 2000 and 2030, the study estimated that vaccination will prevent 120 million deaths, of which 65 million are in children younger than five years. 58 million of deaths would be prevented by measles vaccines and 38 million by hepatitis B vaccines.