Last chance for City
Any lingering hopes Manchester City entertain of getting involved in a Premier League title race in their first full season of being bankrolled from Abu Dhabi will be extinguished if they fail to beat Chelsea on Saturday.
The league leaders arrive at Eastlands with a 14-point advantage over City, who have slipped to seventh after a run of seven consecutive draws.
It already looks like a virtually unbridgeable gap and Chelsea have acquired a distinct air of champions-elect after following up wins over Liverpool and Manchester United earlier in the season with last weekend's 3-0 victory at Arsenal.
United, who trail Chelsea by five points, travel to West Ham while Arsenal will seek to get their campaign back on track at home to Stoke.
Steven Gerrard makes his 500th appearance for Liverpool at Blackburn while third-placed Tottenham travel to Everton on Sunday.
Despite a blip in midweek, when a second string side was knocked out of the League Cup by Blackburn, the confidence in the Chelsea camp was underlined by Portugal defender Ricardo Carvalho, who described the current squad as stronger than the one which won the club's first title in 50 years in 2004-05.
Carvalho was a key figure in what was Jose Mourinho's first season in charge, during which Chelsea lost only one league match and conceded only 15 goals.
City's spirits were lifted by a 3-0 win over Arsenal in the League Cup in midweek and manager Mark Hughes insists there is no reason for his squad to feel overly dissatisfied at being so far off the pace being set by Chelsea.
"We are at a point now where we are reasonably pleased with where we are," Hughes said. "You can't deny we are going in the right direction.
"Comparisons are always made between ourselves and Chelsea. We started from a lot further behind. We need a little bit of time."
Manchester United manager Sir Alex Ferguson must decide whether to retain Darron Gibson, who scored twice as a youthful United side beat Tottenham 2-0 in the League Cup in midweek, for the trip to West Ham.
The likes of Wayne Rooney, Darren Fletcher and Ryan Giggs are expected to return but Ireland midfielder Gibson made a compelling case for promotion to United's first-choice line-up.
Arsenal's frustration over the way their challenge has unravelled following back-to-back defeats by Sunderland and Chelsea has deepened after Theo Walcott was ruled out of Saturday's match with a hamstring injury.
Fixtures
(1500 GMT kick-off unless stated)
Saturday
Arsenal v Stoke City, Aston Villa v Hull, Blackburn v Liverpool, Manchester City v Chelsea (1730 GMT), Portsmouth v Burnley (1245 GMT), West Ham v Manchester Utd, Wigan v Birmingham, Wolves v Bolton
Sunday
Everton v Tottenham (1600), Fulham v Sunderland
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