Jorge Lorenzo, who crashed out of his last two races, turned the tables with his third win of the season Sunday with a MotoGP triumph at Indianapolis Motor Speedway as world champion Valentino Rossi failed to finish.
The 22-year-old Spaniard, who was the series rookie of the year in 2008, won the 28-lap, 118.104 km race by more than nine seconds over runner-up Alex De Angelis of San Marino.
American Nicky Hayden, who finished second in the inaugural Indianapolis race last year, was third, fending off the late challenge of Andrea Dovizioso.
Lorenzo averaged 149.976 km/h on his Yamaha to win in 47min 13.592sec.
De Angelis was 9.435 seconds behind the leader as he earned his first podium finish on the circuit.
Eight-time world champion Rossi of Italy, Lorenzo's Fiat-Yamaha teammate and the current points leader, had his bid for a second consecutive Indianapolis victory come to a premature end when he crashed and slid onto the grass on the 10th lap.
He managed to remount, but soon pitted and walked away.