Djokovic said that his subdued performance on a court where he has won six titles might have been due to the blow suffered while greeting fans on Friday night.
Djokovic's bid for a record-extending 41st Masters 1000 title was ended in just over an hour by Chilean Tabilo, who is ranked 32nd in the world but was hugely impressive and claimed his first win over a top-10 opponent.
Novak Djokovic was left in agony after being struck with a hard plastic water bottle as he left the court following his 6-3, 6-1 win over France's Corentin Moutet at the Rome Open which advanced him to the third round on Friday.
World number one Novak Djokovic said he believes he will be in top form for the French Open and hopes to prove that at the Italian Open which started on Wednesday.
Last month, the Serb ended a five-year partnership with coach Goran Ivanisevic.
The Italian world number two can come within touching distance of the top-ranked Djokovic in the standings should he triumph in Madrid this fortnight and he arrives in the Spanish capital brimming with confidence and carrying an impressive 25-2 win-loss record for the season.
Tennis great Djokovic, a record 24-time Grand Slam champion, equalled his former rival Roger Federer's tally at the prestigeous ceremony in Madrid.
Djokovic has now pulled out of the Madrid Open three times in four years.
Tennis superstar Rafael Nadal said Monday returning to action at the Barcelona Open is a "gift" and he wants to enjoy every moment of what he expects to be the last year of his career.
Casper Ruud finally defeated Novak Djokovic at the sixth attempt on Saturday, setting up a Monte Carlo Masters title showdown with Stefanos Tsitsipas.
An inspired Stefanos Tsitsipas handed Jannik Sinner his second loss of the season on Saturday as the two-time champion reached the Monte Carlo Masters final 6-4, 3-6, 6-4.
Djokovic will take on either Casper Ruud of Norway or France's Ugo Humbert for a place in Sunday's final.
World number one Novak Djokovic said his "feeling was great" as he flew past Roman Safiullin in straight sets at the Monte Carlo Masters on Tuesday, after third seed Carlos Alcaraz withdrew from the event due to injury.
Rafa Nadal's withdrawal from the Monte Carlo Masters has cast doubt over the 22-times Grand Slam champion's participation at the French Open, but Novak Djokovic said he is still hoping for a final chapter in their storied rivalry.
Djokovic has had a poor start to the year by his standards.
Novak Djokovic and Goran Ivanisevic are to go their separate ways, the tennis world number one announced on Wednesday, ending a five-year association which yielded 12 Grand Slams.
World number one Novak Djokovic withdrew from next week's ATP-WTA Miami Open on Saturday in the wake of his shock exit at Indian Wells.
Nardi, ranked 123rd in the world, played superbly to win 6-4, 3-6, 6-3 as Djokovic's return to Indian Wells ended in a stunning third round exit.
World number one Djokovic, who had not played since losing an Australian Open semi-final to Jannik Sinner on January 26, is chasing a sixth title at the desert venue in the season's first Masters event.