Raphael Varane announced on Tuesday he will leave Manchester United at the end of the season when his contract expires following a three-year spell at Old Trafford.
Spurs' lead over the Magpies was cut to 10 points with six games remaining, but Newcastle have a far easier run-in.
Newcastle striker Alexander Isak has been targeted by burglars who stole a car from the Sweden international's home.
Newcastle ended their 13-year wait to beat bitter rivals Sunderland as Alexander Isak's double inspired a 3-0 win in the FA Cup third round on Saturday.
Wood left Newcastle to join Forest in a £15 million ($19 million) deal in June, but had scored only four times for his new club.
PSG drew 1-1 away to Group F winners Borussia Dortmund to go through as runners-up after Milan came from behind to beat Newcastle at St James' Park and eliminate Eddie Howe's side.
Newcastle goalkeeper Nick Pope will be sidelined for "around four months" with a shoulder injury, manager Eddie Howe said on Wednesday as his list of absentees continued to grow.
Newcastle must avoid defeat in the French capital to have any chance of reaching the last 16
"We had to come here, Chelsea, to show that it's going to be difficult for them to play, to win the game and to beat us," said Pochettino
United had suffered five defeats in their previous 10 home games this season, their worst start to a campaign at Old Trafford since 1930-31 when they also lost five of 10 and were relegated from the top flight.
Mikel Arteta branded Arsenal's 1-0 defeat at Newcastle "a disgrace" after Anthony Gordon's winner was controversially allowed to stand by VAR.
Manchester United manager Erik ten Hag looked shell-shocked as his team were booed off the pitch and the Dutchman is under intense pressure following their 3-0 defeat by Manchester City at Old Trafford on Sunday.
A rampant Newcastle United put in a stellar showing to secure a superb 4-1 victory over French champions Paris St Germain in their first Champions League home match in 20 years on Wednesday.
Newcastle came close to matching the Premier League's record margin of victory as they thrashed Sheffield United 8-0 at Bramall Lane on Sunday.
Newcastle held AC Milan to a goalless draw in Tuesday's opening match of their first Champions League campaign in two decades.
Stefano Pioli insisted on Monday that AC Milan have turned their attentions to the Champions League opener with Newcastle United after the local derby humiliation at the weekend.
Paris St Germain will kick off their quest for a maiden Champions League trophy in a strong Group F featuring Borussia Dortmund, AC Milan and Newcastle United following the draw on Thursday.
Liverpool defender Virgil van Dijk has been charged with acting in an improper manner after he was sent off at Newcastle on Sunday.
Darwin Nunez came off the bench to score twice as Liverpool snatched a sensational 2-1 Premier League win at Newcastle United on Sunday, with the visitors bouncing back from a straight red card in the first half for captain Virgil van Dijk.