Diego Demme and Eljif Elmas scored their first Serie A goals as Napoli followed up last weekend’s win over champions Juventus with a 4-2 victory at Sampdoria on Monday.
Gennaro Gattuso’s side claimed back-to-back league wins for just the second time this season to move 10th, two points off the Europa League berths.
But a return to the Champions League remains a distant hope as Napoli remain nine points behind fourth-placed Atalanta and Roma.
Arkadiusz Milik struck early for the visitors, nodding in the first after just three minutes off a cross from fellow Pole Piotr Zielinski.
North Macedonia international Elmas tapped in a second after quarter of an hour for his first goal in Italy’s top flight.
But Sampdoria halved the deficit with Fabio Quagliarella’s powerful volley on 26 minutes.
Gabbiadini pulled Sampdoria level from the penalty spot with 15 minutes to go after Kostas Manolas tripped Quagliarella in the box.
Demme restored Napoli’s advantage seven minutes from time with Dries Mertens sweeping the fourth into an empty net deep into injury time.