The earliest-known horse Sifrhippus, dwarfed next to a modern domestic horse. Source: Live Science

During the Paleocene-Eocene Thermal Maximum, or PETM, about 56 million years ago, a massive release of carbon into the atmosphere and oceans boosted average global temperatures by about 10 degrees Fahrenheit (5.5 degrees Celsius) over 175,000 years. Mammals responded to this climate change by shrinking, with about one-third of species getting smaller.