Former champion Andy Murray defeated France's Jo-Wilfried Tsonga 7-5, 7-5, 6-4 on Monday to reach the quarterfinals of the US Open.
The eighth-seeded Scot booked a clash with world number one Novak Djokovic, the man he beat in the 2012 final at Flushing Meadows for his first Grand Slam title.
Australian Open champion Stan Wawrinka powered into the quarterfinals with a 7-5, 4-6, 7-6 (9/7), 6-2 victory over Tommy Robredo.
The third-seeded Swiss fired 18 aces, saving two set points in the third-set tiebreaker and dominating the fourth set against the 16th-seeded Spaniard.
Murray broke Tsonga in the final game of each set en route to the victory, recovering an early break in both the second and third sets as he battled past the Frenchman, who had beaten him on his way to the title in Toronto in August in their last encounter.
"It was extremely tough conditions, very humid and obviously windy," Murray said. "It started to cool down at the end but the first two sets were very long tough sets."
He broke Tsonga in the next game to get the set back on serve and in the final game gave himself a triple break point with a precise backhand winner.
Tsonga saved one with an overhead, but misfired on the next to end it.
Wawrinka fired 75 winners, including 27 in the third set that surpassed Robredo's total of 19 for the match.
"It was a really tough battle today," said Wawrinka, who also survived a tumble into the courtside seats in Armstrong Stadium when he hit the knee-high board surrounding the court at full stretch for a shot.
"I had some ups and downs physically," he said. "From that I'm OK, I'm more tired from the running, from the match.
"When you win, it's always more easy to feel good after," added Wawrinka, who had won only two of his prior eight matches against Robredo.
One of those victories was in the fourth round of the Australian Open en route to his first Grand Slam title.
He will face either fifth-seeded Canadian Milos Raonic or 10th seeded Kei Nishikori of Japan for a place in the semifinals.